Our Story

About Dewayne Acup

Board-certified family physician with over 12 years of dedicated medical service to the Cape Girardeau, Missouri community.

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Dewayne Acup – Acup Medical Clinic
Meet Dewayne Acup

Healthcare Built on Compassion & Trust

Dewayne Acup is the founder and lead physician of Acup Medical Clinic, located at 1105 Ranney Avenue in Cape Girardeau, Missouri. With over 12 years of clinical experience in family and general medicine, Dewayne has built a strong reputation for delivering thorough, compassionate and genuinely patient-centered care to thousands of families across the Cape Girardeau region.

Dewayne's approach to medicine starts with listening. He believes every patient deserves to be truly heard — not rushed, not overlooked — and that great medical care begins with a genuine human connection. His clinic welcomes patients of all ages, from newborns to seniors, and every visit is treated with the same level of care and attention.

Beyond the clinic, Dewayne is deeply passionate about community health education and preventive medicine. He regularly engages with local organizations to promote healthy lifestyles and believes strongly that empowering patients with knowledge is one of the most powerful tools in modern medicine.

12+ Years in Practice
4,000+ Patients Served
97% Patient Satisfaction
8+ Medical Services
What We Stand For

Our Core Values

Every patient visit, every diagnosis and every treatment plan is built on these deeply held values at Acup Medical Clinic.

Compassionate Care

We treat every patient with genuine warmth, empathy and respect — because great healthcare starts with a human connection.

Clinical Excellence

We maintain the highest standards of medical practice, staying current with evidence-based treatments and best practices.

Open Communication

We believe informed patients make better health decisions. We listen carefully and explain everything in plain language.

Patient Safety

Your safety is our absolute priority. We follow strict clinical protocols to ensure every visit is safe and effective.

Family-Centered

We serve the whole family — building lifelong relationships with every household we are privileged to care for.

Preventive Focus

We prioritize prevention over treatment — helping our patients stay healthy before illness has a chance to develop.

Qualifications

Trained, Certified & Board-Approved

Dewayne Acup's medical expertise is backed by extensive formal education, board certification and over 12 years of hands-on clinical practice in family and general medicine across Missouri.

Doctor of Medicine (MD)

Medical degree from an accredited institution with specialized residency training in family and general medicine.

Board-Certified in Family Medicine

Fully board-certified by the American Board of Family Medicine (ABFM) with ongoing continuing medical education.

BLS & ACLS Certified

Current certification in Basic Life Support and Advanced Cardiovascular Life Support for full emergency readiness.

Chronic Disease Management

Advanced specialized training in managing diabetes, hypertension, asthma, heart disease and other long-term conditions.

Pediatric Care Training

Specialized training in infant, child and adolescent healthcare including vaccinations and developmental monitoring.

Acup Medical Clinic environment
Board Certified Physician
Patient Reviews

Trusted by Cape Girardeau Families

The greatest measure of our work is the trust and confidence of the patients and families we are proud to serve every single day.

"Dewayne has been my family doctor for 6 years. He is thorough, patient and genuinely cares about your wellbeing. Best doctor in Cape Girardeau without a doubt."

NW
Nicole W.
Cape Girardeau, MO

"I switched to Dewayne three years ago and it was the best health decision I've made. He takes his time, listens carefully and always follows through."

RG
Robert G.
Jackson, MO

"My kids absolutely love Dr. Acup. He has a wonderful way of making children feel safe and comfortable. Our whole family now sees him regularly."

AM
Angela M.
Sikeston, MO
Where We Serve

Serving Cape Girardeau & Surrounding Missouri

Acup Medical Clinic proudly serves patients across Cape Girardeau and the greater southeast Missouri region.

Cape Girardeau, MO

Our home clinic at 1105 Ranney Ave. Serving all Cape Girardeau residents and surrounding zip codes.

Jackson, MO

Accepting patients from Jackson and surrounding Cape Girardeau County communities.

Sikeston, MO

Trusted medical care available to patients and families throughout the Sikeston area.

Perryville, MO

Serving the Perryville community with the same high standard of compassionate patient care.

Scott City, MO

Providing comprehensive family medical services to patients from Scott City and nearby areas.

Surrounding Areas

Not listed? Call (618) 615-5153 — we welcome patients from all across southeast Missouri.

Ready to Become a Patient?

Book your first appointment with Dewayne Acup today. New patients are always welcome at Acup Medical Clinic in Cape Girardeau, Missouri.

Book an Appointment (618) 615-5153